BIMOLECULAR DISPLACEMENT MECHANISMS: In nucleophilic aromatic substitution (S_NAr) reactions, there are two general mechanisms that describe the bimolecular displacement of a leaving group by a nucleophile on an aromatic ring. These mechanisms are known as the Addition-Elimination (AE) mechanism and the Elimination-Addition (EA) mechanism.
PATH: PHARMD/PHARMD NOTES/ PHARMD FIRST YEAR NOTES/ ORGANIC CHEMISTRY/ PHARMACEUTICAL ORGANIC CHEMISTRY/ BIMOLECULAR DISPLACEMENT MECHANISMS, ORIENTATION, ALIPHATIC VS AROMATIC NUCLEOPHILIC SUBSTITUTION.