Tests based upon abnormalities of serum proteins are diagnostic examinations that assess the levels and characteristics of proteins in the bloodstream. Proteins play essential roles in various bodily functions, including transportation of molecules, immune responses, and maintenance of tissue structure. Abnormalities in serum proteins can indicate underlying health conditions, such as liver diseases, kidney disorders, inflammation, or certain cancers. In this article, we will explore the significance of tests based upon abnormalities of serum proteins, the components measured, and their applications in assessing protein levels and disorders.