The Michael addition is a versatile organic reaction that involves the nucleophilic addition of a nucleophile to a conjugated acceptor system, typically an α,β-unsaturated carbonyl compound. The reaction is named after Arthur Michael, the American chemist who first described this transformation.
PATH: PHARMD/PHARMD NOTES/ PHARMD FIRST YEAR NOTES/ ORGANIC CHEMISTRY/ PHARMACEUTICAL ORGANIC CHEMISTRY/ MICHAEL ADDITION.