The Kolbe reaction, also known as the Kolbe-Schmitt reaction, is a carboxylation reaction that involves the electrolysis of a phenol or phenoxide salt in the presence of carbon dioxide (CO2). It was discovered by Hermann Kolbe in the 19th century and is named after him.

PATH: PHARMD/PHARMD NOTES/ PHARMD FIRST YEAR NOTES/ ORGANIC CHEMISTRY/ PHARMACEUTICAL ORGANIC CHEMISTRY/KOLBE REACTION.

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