Pre-clinical evaluations play a critical role in the early stages of drug development. Before a new drug can be tested on human subjects, it undergoes a rigorous evaluation process to assess its safety, efficacy, and pharmacokinetic properties. These evaluations provide essential data that guide researchers and regulators in determining whether a drug has the potential to advance to clinical trials. In this article, we will explore the importance of pre-clinical evaluations and the key aspects involved in this stage of drug development.