Congestive heart failure (CHF) is a chronic condition characterized by the heart’s inability to pump blood effectively. It can result from various underlying causes, such as coronary artery disease, hypertension, or heart valve disorders. The management of CHF involves a comprehensive approach that includes lifestyle modifications and medications. In this article, we will explore the drugs commonly used in the therapy of congestive heart failure, their mechanisms of action, and their role in improving symptoms and quality of life for patients.