Gluconeogenesis is a critical process in carbohydrate metabolism that enables the synthesis of glucose from non-carbohydrate precursors. It occurs primarily in the liver and to a lesser extent in the kidneys, providing an essential mechanism for maintaining glucose homeostasis during periods of fasting, prolonged exercise, or low carbohydrate intake. This article explores the process of gluconeogenesis, its key steps, regulation, and its significance in carbohydrate metabolism.

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