Parkinsonism is a complex neurological disorder that affects movement and is characterized by symptoms such as tremors, rigidity, and bradykinesia (slowness of movement). It is primarily caused by the degeneration of dopamine-producing cells in the brain, particularly in a region called the substantia nigra. In this article, we will explore the etiopathogenesis of Parkinsonism, including its underlying mechanisms, and discuss the pharmacotherapy options used in its treatment.