Powders and granules are commonly used dosage forms in pharmaceuticals and various industries. They offer advantages such as ease of administration, increased stability, and enhanced solubility. Understanding their classification, advantages, disadvantages, preparation methods, and applications is crucial for ensuring safe and effective use. In this article, we will explore the classification of powders and granules, their advantages and disadvantages, preparation techniques, and specific applications in the form of insufflations, dusting powders, eutectic and explosive powders, tooth powders, and effervescent powders and granules.