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KINETICS OF SECOND AND FIRST ORDER REACTION
  • Pharmaceutical Organic Chemistry

8. KINETICS OF SECOND AND FIRST ORDER REACTION

Nuclophilic aliphatic substitution mechanism: Nucleophiles and leaving groups, kinetics of second and first order reaction, mechanism and kinetics of SN2 reactions. Stereochemistry and steric hindrance, role of solvents, phase transfer…

MECHANISM AND KINETICS OF SN2 REACTIONS
  • Pharmaceutical Organic Chemistry

9. MECHANISM AND KINETICS OF SN2 REACTIONS

Nuclophilic aliphatic substitution mechanism: Nucleophiles and leaving groups, kinetics of second and first order reaction, mechanism and kinetics of SN2 reactions. Stereochemistry and steric hindrance, role of solvents, phase transfer…

MECHANISM AND KINETICS OF SN1 REACTIONS
  • Pharmaceutical Organic Chemistry

10. MECHANISM AND KINETICS OF SN1 REACTIONS

Nuclophilic aliphatic substitution mechanism: Nucleophiles and leaving groups, kinetics of second and first order reaction, mechanism and kinetics of SN2 reactions. Stereochemistry and steric hindrance, role of solvents, phase transfer…

1,2 elimination, E2 and E1 mechanism
  • Pharmaceutical Organic Chemistry

11. Dehydrohalogenation of alkyl halides – 1,2 elimination, kinetics, E2 and E1

Dehydrohalogenation of alkyl halides: 1,2 elimination, kinetics, E2 and E1 mechanism, elimination via carbocation, evidence for E2 mechanism, absence of rearrangement isotope effect, absence hydrogen exchange, the element effect, orientation…

Evidence for E2 mechanism, absence of rearrangement isotope effect, absence hydrogen exchange, the element effect, orientation and reactivity
  • Pharmaceutical Organic Chemistry

12. Evidence for E2 mechanism, absence of rearrangement isotope effect, absence hydrogen exchange, the element effect, orientation and reactivity

Dehydrohalogenation of alkyl halides: 1,2 elimination, kinetics, E2 and E1 mechanism, elimination via carbocation, evidence for E2 mechanism, absence of rearrangement isotope effect, absence hydrogen exchange, the element effect, orientation…

E2 VERSUS E1, ELIMINATION VERSUS SUBSTITUTION
  • Pharmaceutical Organic Chemistry

13. E2 VERSUS E1, ELIMINATION VERSUS SUBSTITUTION

Dehydrohalogenation of alkyl halides: 1,2 elimination, kinetics, E2 and E1 mechanism, elimination via carbocation, evidence for E2 mechanism, absence of rearrangement isotope effect, absence hydrogen exchange, the element effect, orientation…

DEHYDRATION OF ALCOHOL, EASE OF DEHYDRATION, ACID CATALYSIS, REVERSIBILITY, ORIENTATION
  • Pharmaceutical Organic Chemistry

14. DEHYDRATION OF ALCOHOL, EASE OF DEHYDRATION, ACID CATALYSIS, REVERSIBILITY, ORIENTATION

Dehydrohalogenation of alkyl halides: 1,2 elimination, kinetics, E2 and E1 mechanism, elimination via carbocation, evidence for E2 mechanism, absence of rearrangement isotope effect, absence hydrogen exchange, the element effect, orientation…

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