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PHARMD GURU
  • Home
  • First year subjects
    • Anatomy and physiology
    • Pharmaceutics
    • Medicinal Biochemistry
    • Pharmaceutical Inorganic Chemistry
    • Pharmaceutical Organic Chemistry
    • Remedial Mathematics
  • Second year subjects
    • Pathophysiology
    • Pharmaceutical Microbiology
    • Pharmacognosy and Phytopharmaceuticals
    • Pharmacology-1
    • Community Pharmacy
    • Pharmacotherapeutics-1
  • Third year subjects
    • Pharmacology-2
    • Pharmaceutical Analysis
    • Pharmacotherapeutics-2
    • Pharmaceutical Jurisprudence
    • Medicinal Chemistry
    • Pharmaceutical Formulations
  • Fourth year subjects
    • Pharmacotherapeutics-3
    • Hospital Pharmacy
    • Clinical Pharmacy
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WITTIG REACTION
  • Pharmaceutical Organic Chemistry

29. WITTIG REACTION

Wittig Reaction The Wittig Reaction is a very important method in organic chemistry for creating alkenes. It was discovered by Georg Wittig in 1954. In this reaction, a special compound…

MICHAEL ADDITION
  • Pharmaceutical Organic Chemistry

30. MICHAEL ADDITION

Introduction Michael Addition (also called the Michael Reaction) is an important organic reaction used to form carbon–carbon bonds. It is a nucleophilic addition where a carbon nucleophile adds to an…

HOFMANN REARRANGEMENT
  • Pharmaceutical Organic Chemistry

31. HOFMANN REARRANGEMENT

Hofmann Rearrangement Hofmann Rearrangement (also called Hofmann Degradation or Hofmann Bromamide Reaction) is a chemical reaction where a primary amide is converted into a primary amine using bromine and a…

SANDMEYERS REACTION
  • Pharmaceutical Organic Chemistry

32. SANDMEYERS REACTION

32. Sandmeyer’s Reaction The Sandmeyer’s Reaction is a very important method in organic chemistry used to convert an aromatic amine into an aryl halide. It is especially useful when direct…

BASICITY OF AMINES
  • Pharmaceutical Organic Chemistry

33. BASICITY OF AMINES

Basicity of Amines Amines behave as bases because the nitrogen atom contains a lone pair of electrons. This lone pair can accept a proton (H⁺), making amines reasonably strong organic…

DIAZOTISATION AND COUPLING
  • Pharmaceutical Organic Chemistry

34. DIAZOTISATION AND COUPLING

DIAZO COMPOUNDS Diazo compounds contain the N=N group. Their general structure is R-N=N-R’. Usually both R and R’ are aromatic groups, which help stabilize the azo group by delocalization. These…

ACIDITY OF PHENOLS
  • Pharmaceutical Organic Chemistry

35. ACIDITY OF PHENOLS

Acidity of Phenols Phenols are weakly acidic organic compounds. They can donate a proton (H⁺) from their –OH group, forming a phenoxide ion. Their acidity is stronger than alcohols but…

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